Past Research Studies by Dr. Farr

Prior Clinical Studies:

  • Justifying Patellar Instability Treatment by Early Results (JUPITER)

  • MOCA (Metrics of Osteochondral Allografts) REGISTRY

  • Samumed, LLC / “A Study to Support the Radiographic Eligibility Screening Process of Samumed Studies in Symptomatic Knee Osteoarthritis Subjects” Protocol Number: SM04690-OA-15

  • Samumed, LLC “A Phase 3, 28-Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of a Single Injection of SM04690 Injected in the Target Knee Joint of Moderately to Severely Symptomatic Osteoarthritis Subjects” SM04960-OA-10 (STRIDES_1)

  • Episealer® Knee System IDE Clinical Study: A Prospective, Randomized, Controlled, Multi-Center Study to Evaluate the Safety and Effectiveness of the Episealer® Knee System Compared to Microfracture for the Treatment of Focal Femoral Knee Chondral or Osteochondral Lesion

Surgical Outcome Studies:

  • Anterior Cruciate Ligament Reconstruction

  • Anteromedialization (AMZ)

  • MACI Implantation/ Articular Cartilage Implantations

  • Fresh Osteochondral Shell Transplantation

  • High Tibial Osteotomy

  • Medial Patellofemoral Ligament Reconstructions

  • Meniscal Transplantation

  • Patellofemoral Arthroplasty

  • Total Knee Arthroplasty

Completed Studies:

  • A randomized, placebo-controlled, patient and investigator blinded, Proof of Concept study investigating the safety, tolerability and preliminary efficacy of multiple intra-articular LNA043 injections in regenerating the articular cartilage of the knee in patients with articular cartilage lesions

  • A Post Market,Single Blind, MultiCenter, Randomized, Controlled Trial of Hymovis Intra-Articular Injections in Active Subjects with Knee OsteoArthritis (Phase IV)

  • Evaluation of the ReNu Amniotic Suspension Allograft after Marrow Stimulation in the Treatment of Osteochondral Defects

  • Determining the Minimal Clinical Important Difference (MCID) and Patient Acceptable Symptomatic State (PASS) for Patients Undergoing Articular Procedures of the Knee

  • Multi-Center Experience with ACI in the Patellofemoral Compartment

  • Decreased Re-intervention Rate with Collagen Membrane ACI

  • A Prospective Double Blinded, MultiCenter, Randomized, Controlled Trial to Evaluate Mechanical Debridement vs. Radiofrequency-Based Debridement in the Treatment of Articular Cartilage Lesions

  • NeoCart: A Randomized Comparison of Neocart to Microfracture for the Repair of Articular Cartilage Injuries in the Knee

  • An Investigation of ReNu™ Knee Injection: Monitoring the Response of Knee Function and Pain in Patients with OsteoArthritis

  • Longitudinal Histologic Assessment and Gen Expression Profiling of Healing Cartilage Defects

  • Prospective, MultiCenter Single Arm Pilot Study To Evaluate Symptom Relief in Patients with Medial Knee OsteoArthritis (OA) Treated with the KineSpringÒ Knee Implant for Load Reduction (SOAR)

  • Knee Creations SCPÒ Observational Cohort Follow-up Study

  • Prospective Efficacy Evaluation of Subchondroplasty™ for the Treatment of Defects Associated with Tibial Marrow Lesions

  • Validity of an Interactive Technique for Collecting Patient Reported Outcomes of Orthopaedic Procedures

  • A Post-Market, Longitudinal Data Collection Study of Articular Cartilage Defects of the Knee Treated with Denovo® NT Natural Tissue Graft Protocol#CSU2010-22B

  • A Post Market Study to Evaluate the Chondrofix Osteochondral Allograft Utilized for Treatment of Subjects with Cartilage Lesions in the Knee

  • AANA: Acute Complications of Knee and Shoulder Arthroscopy

  • A Feasibility Study to Determine the Up-Regulation of Anti-inflammatory Cytokines in Whole Blood From Patients with Osteoarthritis

  • A Multicenter, Randomized, Pivotal Study to Evaluate the Safety and Efficacy of the Cartilage Autograft Implantation System (CAIS) for the Surgical Treatment of Articular Cartilage Lesion of the Knee

  • A Long-Term Follow-up Study of Chondrogen™ Adult Universal Cell Delivered by Intra-articular Injection Following Meniscectomy in Patients 18-60 Years

  • Regeneration Technologies, Inc. Registry of Biocleanse® Meniscus Transplants

  • A Post Market Study of Articular Cartilage Defects of the Knee Treated with DeNovo® NT, Natural Tissue Graft.

  • An Open-Label Phase I/II Pilot Study to Evaluate Articular Cartilage Defects of the Knee with a Neocartilage Implant

  • Collection of Specimens from Joint Replacement Surgery for In-Vitro Osteoarthritis Research

  • Evaluation Outcomes After Standard of care Operative and Non-operative Management of the Knee 20 Year Follow-up